Who We Are
Novadigm is a patient-centered clinical initiative supporting individuals who continue to decline, remain symptomatic, or face terminal guidance despite receiving best guideline-directed medical care. We step in when conversations shift toward hospice, palliation, or hopelessness.
Hope Beyond Limits
We are dedicated to complex, refractory, Stage-IV and end-stage disease cases where conventional systems failed.
Decades of Science
Built on over 30 years of translational research converted into real bedside medicine.
PRISM
We integrate ancient VPK intelligence with modern diagnostics, regenerative medicine, systems biology and decision AI.
Redefining Health
Novadigm is a pioneering healthcare center offering Institute of Poly Scientific Regenerative Integrative Systems Medicine (PRISM), redefining modern healthcare by merging ancient wisdom with contemporary medical innovation. We believe true healing requires a holistic, personalized, and deeply scientific approach.
Our Vision
We envision a world where healthcare is truly individualized — where each person’s unique health profile is deeply understood and treated through a thoughtful blend of traditional Ayurvedic wisdom and state-of-the-art diagnostics.
Our Mission
Our mission is to deliver a transformative healthcare experience by integrating time-honored Ayurvedic principles with cutting-edge diagnostic technologies, empowering individuals to lead healthier and more balanced lives.
Our Leadership
Ms. Santhi Uppalapati
Operations Manager
Dr. Ravishankar Polisetty
Strategic, Technology & Clinical Leadership
Mr. Duvvuri Sastry
Manufacturing
Our Clinical Approach
Every patient journey begins with comprehensive evaluation, deep counseling and the advanced VPK-42 metabolic fingerprinting framework to design precision-tailored healthcare.
Deep Assessment
Holistic systems evaluation & neuro-humoral mapping.
Precision Care
Personalized medication, nutritional design, exercise alignment and regulation protocols.
Commitment to Healing
Beyond treatment — we stand committed to restoring life and health potential.
Global Impact & Clinical Success
28,000+ patients | 63% end-stage survival among compliant cases | 95% quality-of-life improvement | USD $5M+ healthcare innovation revenue
Global Presence & Expansion
Patients served across India, Russia, UK, Germany, Canada & USA. Strategic collaborations include IIT Hyderabad, Johns Hopkins, British College of Ayurveda, University of Waterloo ecosystem, and international policy leadership recognition including UK Parliament & European Parliament.
Clinical Intelligence & Decision Science
Within the University of Waterloo innovation ecosystem, complex biological and physiological observations were translated into mathematical and computational models—now recognized as clinical data science and AI-driven decision intelligence.
Add a Patient State Mapping title
Multidimensional clinical state representation.
Predictive Vulnerability Modeling
Early identification of risk and disease trajectories.
ERP-Integrated Systems
Enterprise-grade clinical decision-support integration.
Technology Launch & Global Expansion
Following the launch of Docture Poly—an AI-enabled wearable clinical intelligence platform— at TAVES (Canada), Novadigm Health Inc. was incorporated as a Delaware entity with a registered California franchise, enabling a scalable U.S. hub-and-spoke care model.
Academic, Institutional & Policy Leadership
Strategic collaborations include IIT Hyderabad (I-PRISM framework), Johns Hopkins University, and the British College of Ayurveda. Founder Dr. Ravishankar Polisetty has delivered five presentations in the UK House of Commons, one in the House of Lords, received two invitations to the European Parliament, and was accredited in March 2025 as a recognized medical expert within the European Parliament. He currently serves as Vice Chair – Precision Medicine, EICBI.