Overview

Ankylosing Spondylitis is a chronic inflammatory form of arthritis that primarily affects the spine. It causes persistent inflammation in the joints between the vertebrae and the sacroiliac joints. Over time, this inflammation may lead to fusion of the spinal bones. The condition typically begins in early adulthood. It may cause lower back pain and stiffness that worsens after rest. Ankylosing spondylitis can also affect other joints and, in some cases, the eyes and heart. The severity varies among individuals. The condition progresses gradually over years. Early diagnosis helps prevent structural damage. Long-term monitoring is essential to manage disease activity.

What Happens During Allergic Rhinitis?

Inflammation develops in the spinal joints and surrounding ligaments. The body attempts to repair this inflammation by forming new bone. Excess bone formation may cause adjacent vertebrae to fuse. This reduces spinal flexibility and may result in a rigid posture. Chronic inflammation can also affect other joints.

Diagnosis

Diagnosis involves clinical evaluation of back pain and stiffness patterns. Imaging studies such as X-rays or MRI detect inflammation and spinal changes. Blood tests may identify inflammatory markers and genetic markers such as HLA-B27. Diagnosis is based on clinical and imaging findings.